In Rat Model, Social Isolation Leads To Greater Vulnerability To Addiction

Rats that are socially isolated during a critical period of adolescence are more vulnerable to addiction to amphetamine and alcohol, found researchers at The University of Texas at Austin. Amphetamine addiction is also harder to extinguish in the socially isolated rats. These effects, which are described this week in the journal Neuron, persist even after the rats are reintroduced into the community of other rats. "Basically the animals become more manipulatable," said Hitoshi Morikawa, associate professor of neurobiology in the College of Natural Sciences...

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