Paving The Way For Protein Drugs From Bacteria

A cheaper, more efficient technique for developing complex protein drugs from bacteria has been developed at the University of Sheffield. Using the bacterium E. coli, researchers from the University's Faculty of Engineering showed it was possible to vastly increase the efficiency of the cells producing specifically modified proteins, as well as improve its performance and stability. The modification is present in over two-thirds of human therapeutic drugs on the market and involves the addition of specific sugar groups to the protein backbone, a process termed glycosylation...

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