Source: http://feedproxy.google.com/~r/mnt/healthnews/~3/OHAsyaQfXGA/251352.php
Sunday, 14 October 2012
Targeting Dual Roles Of PARP-1 May Slow Cancer Growth And Progression
A newly discovered function of PARP-1 could be the key to more effective therapeutics to treat advanced prostate cancer patients, a recent preclinical study published in Cancer Discovery by Jefferson's Kimmel Cancer Center researchers suggests. The team, led by Karen E. Knudsen, Ph.D., Professor in the Departments of Cancer Biology, Urology, & Radiation Oncology at Thomas Jefferson University, found that functions of PARP-1 not only include DNA damage repair but also androgen receptor (AR) regulation in advanced prostate cancer growth and progression...
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