How living cells solved a needle in a haystack problem to produce electrical signals

Filtered from a vast sodium sea, more than 1 million calcium ions per second gush through our cells' pores to generate chargesScientists have figured out how calcium channels - the infinitesimal cell membrane pores that generate electrical signals by gating a charged-particle influx - have solved a "needle in a haystack" problem.The solution to the longstanding riddle is reported in the advanced online edition of Nature by University of Washington and Howard Hughes Medical Institute investigators. Dr. Ning Zheng, a noted X-ray crystallographer, and Dr.

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