Gene Identified That Controls Aggressiveness In Breast Cancer Cells

In a discovery that sheds new light on the aggressiveness of certain breast cancers, Whitehead Institute researchers have identified a transcription factor, known as ZEB1, that is capable of converting non-aggressive basal-type cancer cells into highly malignant, tumor-forming cancer stem cells (CSCs). Intriguingly, luminal breast cancer cells, which are associated with a much better clinical prognosis, carry this gene in a state in which it seems to be permanently shut down...

Source: http://feedproxy.google.com/~r/mnt/healthnews/~3/3K9HtKLmfas/262898.php

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