Combating muscle wasting and obesity by tweaking energy consumption

Using a new technique to evaluate working muscles in mice, researchers have uncovered physiological mechanisms that could lead to new strategies for combating metabolism-related disorders like muscle wasting and obesity. The study appears in The Journal of General Physiology.ATP-sensitive potassium (KATP) channels, which link membrane excitability to cell metabolism, are abundant in skeletal muscle and play an important role in regulating muscle function and energy consumption.

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