In Parkinson's Disease, Blocking LRRK2 Activity Is Not A Simple Answer

Mutations in the LRRK2 gene are the most common cause of genetic Parkinson's disease (PD). New research published in BioMed Central's open access journal Molecular Neurodegeneration demonstrates that loss of function of LRRK2 (by deletion of the kinase domain) leads to changes in motor co-ordination and causes anxiety-like behaviors and kidney degeneration in mice without affecting dopamine-mediated brain activity. The protein LRRK2 is involved in regulating the structure and function of neurons...

Source: http://feedproxy.google.com/~r/mnt/healthnews/~3/8Nk3s-9EJGc/245968.php

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