PurposeTo determine the long-term impact of stereotactic radiotherapy (SRT) on the quality of life (QoL) of inoperable patients with early-stage non-small cell lung cancer (NSCLC).Methods and materialsFrom January 2006 to February 2008, 39 patients with pathologically confirmed T1-2N0M0 NSCLC were treated with SRT. QoL, overall survival and local tumor control were assessed. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ)-C30 and the lung cancer-specific questionnaire QLQ-LC13 were used to investigate changes in QoL. Assessments were done before treatment, at 3�weeks, every 2?3 months during the first two years, and then every 6�months until 5�years after the treatment or death or progressive disease. The median follow up was 38�months.
Results:
During the 5�years after treatment with SRT for stage I NSCLC, the level of QoL was maintained: There was a slow decline (slope: ?0.015) of the global health status over the 5�years (p?Source: http://www.ro-journal.com/content/10/1/98
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