Of the various SJW constituents, hyperforin appeared to be the most effective in activating CYP isotypes. Pal and Mitra (2006) also found that the flavonoids kaempferol and quercetin showed enhanced expression of CYP3A4 messenger ribonucleic acid (mRNA) in Caco-2 cells. In contrast, hypericin had no effect on any of the CYP isotypes tested. The ability [...]
Source: http://www.ca-medicalnews.com/hypericum-perforatum-cytochrome-p450-part-2.html
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