More Effective Treatment Strategies Likely With Improved Knowledge Of The Physical Basis Of Sickle Cell Disease

Sickle cell disease - the most common inherited blood disorder in the United States - causes red blood cells to distort into a crescent shape and block small blood vessels. New insights into how these abnormal cells disrupt circulation could lead to more effective treatment strategies, as revealed by a study published by Cell Press in the Biophysical Journal. "Sickle cell disease entails a central mechanical component, since the circulation gets blocked," explains senior study author Frank Ferrone of Drexel University...

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